Calculators & quick screens
Working tools, not black boxes.
Browser-based calculators we use ourselves. Each shows the inputs, the assumptions, and the formula — so you can audit the answer before you act on it.
Browser-based calculators we use ourselves. Each shows the inputs, the assumptions, and the formula — so you can audit the answer before you act on it.
Permitted Daily Exposure and Occupational Exposure Limit derivation following EMA Q&A and ICH Q3C principles. Adjustment factors transparent and editable — the file lands defensibly the first time.
Acceptable Intake derivation for nitrosamine impurities under the EMA NDSRI Q&A — (Q)SAR-aware, structure-specific, with read-across reasoning surfaced for the response letter.
Triage a substance against the OECD Conceptual Framework. In silico flags and authority-list signals across EATS modalities — for early-stage portfolio review, not regulatory submission.
Persistence, bioaccumulation and toxicity criteria check against REACH Annex XIII and ECHA R.11 guidance — with PMT/vPvM overlay per the 2023 CLP hazard classes. Each axis (P, B, T, M) carries its own evidence trail and colour-coded verdict.
These calculators are working tools — not regulatory submissions.
They give you a defensible first answer in minutes, with all assumptions on the table. For dossier-grade work, every output should be reviewed and adapted by a qualified toxicologist with access to the full study record. We're happy to do that for you — that's the day job.